(S)-BAY 2965501

Names

[ CAS No. ]:
2732902-09-7

[ Name ]:
(S)-BAY 2965501

Biological Activity

[Description]:

(S)-BAY 2965501 is the left-handed isomer of BAY 2965501 (HY-153343). BAY 2965501 is a potent and selective diacylglycerol kinase zeta (DGKζ) inhibitor. BAY 2965501 induces pERK activation. BAY 2965501 can be used for the research of cancer[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> MAPK/ERK Pathway >> ERK
Signaling Pathways >> Stem Cell/Wnt >> ERK

[Target]

DGKz[1]


[References]

[1]. Schubert N, et al. Phosphorylated extracellular signal-regulated kinase (pERK) activation in T effector cells as a target engagement biomarker for the DGK味 inhibitor BAY2965501 in clinical trials. Cancer Research, 2023, 83(7_Supplement): 2116-2116.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H19FN4O3S

[ Molecular Weight ]:
414.45

Related Compounds