LONP1-IN-2

Names

[ CAS No. ]:
2729981-17-1

[ Name ]:
LONP1-IN-2

Biological Activity

[Description]:

LONP1-IN-2 (compound 9d) is a potent and selective LONP1 inhibitor with IC50 values of 0.187 μM and >10 μM for LONP1 and 20S proteasome, respectively. LONP1-IN-2 can be used in research of cancer[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Kingsley LJ, et, al. Structure-Based Design of Selective LONP1 Inhibitors for Probing In Vitro Biology. J Med Chem. 2021 Apr 22;64(8):4857-4869.  

Chemical & Physical Properties

[ Molecular Formula ]:
C16H27BN4O4

[ Molecular Weight ]:
350.22

Related Compounds

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