Metelimumab

Names

[ CAS No. ]:
272780-74-2

[ Name ]:
Metelimumab

Biological Activity

[Description]:

Metelimumab (CAT-192) is a human IgG4 monoclonal antibody that can selectively neutralize TGFβ1[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[Target]

TGFβ1[1]

[In Vitro]

Metelimumab (0.5 pg/mL-50 μg/mL) 抑制 A549 细胞中 TGFβ1 刺激的 IL-11 产生[1]。

[References]

[1]. Lord DM, et, al. Structure-based engineering to restore high affinity binding of an isoform-selective anti-TGFβ1 antibody. MAbs. 2018 Apr;10(3):444-452.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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