4H-1,3,2-Oxazaphosphorin-4-one,2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide
Names
[ CAS No. ]:
27046-19-1
[ Name ]:
4H-1,3,2-Oxazaphosphorin-4-one,2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide
[Synonym ]:
Oxo-Endoxan
4-Ketocyclophosphonamid
4-Ketocyclophosphamide
2-(Bis(2-chloroethyl)amino)tetrahydro-4H-1,3,2-oxazaphosphorin-4-one 2-oxide
4-ketocyclophosphamide mustard
Asta 5160
4H-1,3,2-Oxazophosphorin-4-one,2-(bis(2-chloroethyl)amino)tetrahydro-,2-oxide
4-Oxocyclophosphamide
2-<Bis(2-chlorethyl)amino>-4-oxo-tetrahydro-2H-1,3,2-oxazaphosphorin-2-oxid
Chemical & Physical Properties
[ Density]:
1.42g/cm3
[ Molecular Formula ]:
C7H12Cl2NO4P
[ Molecular Weight ]:
276.05400
[ Exact Mass ]:
274.98800
[ PSA ]:
65.65000
[ LogP ]:
1.49000
[ Index of Refraction ]:
1.515
[ Storage condition ]:
-20°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RQ5857500
- CHEMICAL NAME :
- 4H-1,3,2-Oxazophosphorin-4-one, 2-(bis(2-chloroethyl)amino)tetrahydro-, 2-oxide
- CAS REGISTRY NUMBER :
- 27046-19-1
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C7-H13-Cl2-N2-O3-P
- MOLECULAR WEIGHT :
- 275.09
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 100 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 129,47,1984