CARBENICILLIN PHENYL SODIUM

Names

[ Name ]:
CARBENICILLIN PHENYL SODIUM

[Synonym ]:
Carfecilina [INN-Spanish]
Carfecilline
(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(3-oxo-3-phenoxy-2-phenylpropanoyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Carbenicillin phenyl
Carfecilline [INN-French]
Carfecillinum
Carfecillinum [INN-Latin]
Carbenicillin phenyl ester
Carfecilina

Chemical & Physical Properties

[ Density]:
1.44g/cm3

[ Boiling Point ]:
770.9ºC at 760mmHg

[ Molecular Formula ]:
C₂₃H₂₂N₂O₆S

[ Molecular Weight ]:
454.49600

[ Flash Point ]:
420ºC

[ Exact Mass ]:
454.12000

[ PSA ]:
141.80000

[ LogP ]:
2.78570

[ Vapour Pressure ]:
5.33E-25mmHg at 25°C

[ Index of Refraction ]:
1.672

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ON9109000

CHEMICAL NAME :: Malonamic acid, N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3 .2.0)hept-6-yl)-2- phenyl-, 1-phenyl ester

CAS REGISTRY NUMBER :: 27025-49-6

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C23-H22-N2-O6-S

MOLECULAR WEIGHT :: 454.53

WISWESSER LINE NOTATION :: T45 ANV ESTJ CMVYR&VOR& F1 F1 GVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 980 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher information, see AMBIEH. Volume(issue)/page/year: 25,513,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3924 mg/kg

TOXIC EFFECTS :: Blood - agranulocytosis Blood - thrombocytopenia

REFERENCE :: ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher information, see AMBIEH. Volume(issue)/page/year: 25,513,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 728 mg/kg

TOXIC EFFECTS :: Blood - agranulocytosis Blood - thrombocytopenia

REFERENCE :: ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher information, see AMBIEH. Volume(issue)/page/year: 25,513,1980

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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