POLYCYTIDYLIC ACID (5') POTASSIUM SALT

Names

[ Name ]:
POLYCYTIDYLIC ACID (5') POTASSIUM SALT

[Synonym ]:
Potassium 5'-O-(hydroxyphosphinato)cytidine
MFCD00131956
5'-Cytidylic acid, potassium salt (1:1)

Biological Activity

[Description]:

Polycytidylic acid potassium is an immunostimulant and synthetic double-stranded RNA. Polycytidylic acid potassium can be used experimentally to model viral infections in vivo. Polycytidylic acid potassium is a common tool in immune system research[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Marie-Eve Fortier, et al. The viral mimic, polyinosinic:polycytidylic acid, induces fever in rats via an interleukin-1-dependent mechanism. Am J Physiol Regul Integr Comp Physiol. 2004 Oct;287(4):R759-66.

Chemical & Physical Properties

[ Molecular Formula ]:
C₉H₁₃KN₃O₈P

[ Molecular Weight ]:
361.287

[ Exact Mass ]:
361.007721

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Mutational analysis of vaccinia virus E3 protein: the biological functions do not correlate with its biochemical capacity to bind double-stranded RNA.

J. Virol. 89(10) , 5382-94, (2015)

Vaccinia E3 protein has the biochemical capacity of binding to double-stranded RNA (dsRNA). The best characterized biological functions of the E3 protein include its host range function, suppression o...

Related Compounds

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