2,3-diaminotoluene

Names

[ Name ]:
2,3-diaminotoluene

[Synonym ]:
ZR BZ C1
1,2-diamino-3-methylbenzene
3-methylphenylene-1,2-diamine
2,3-Diaminotoluene
2,3,5,6-TETRAFLUORO-4-(TRIFLUOROMETHYL)PHENYLACETIC ACID
VIC-O-TOLYLENEDIAMINE
2,3-Toluylenediamine
3-Methyl-1,2-benzenediamine
Toluene-2,3-diamine
Tolylene-2,3-diamine
3-Methylbenzene-1,2-diamine
3-methyl-1,2-phenylenediamine
2,3-TOLUENEDIAMINE
3-methyl-o-phenylenediamine
EINECS 220-248-5
MFCD00011589
2-amino-3-methylaniline
2,3-Tolylenediamine
ORTHO-DIAMINOTOLUENE
2,3-Toluilenediamine
3-methyl-1,2-diaminobenzene
1,2-Benzenediamine, 3-methyl-

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
255.0±0.0 °C at 760 mmHg

[ Melting Point ]:
59-65 °C(lit.)

[ Molecular Formula ]:
C₇H₁₀N₂

[ Molecular Weight ]:
122.168

[ Flash Point ]:
131.1±21.3 °C

[ Exact Mass ]:
122.084396

[ PSA ]:
52.04000

[ LogP ]:
0.51

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.636

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XS9550000

CHEMICAL NAME :: Toluene-2,3-diamine

CAS REGISTRY NUMBER :: 2687-25-4

BEILSTEIN REFERENCE NO. :: 0907184

LAST UPDATED :: 199710

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C7-H10-N2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 286 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GPOLA4 Genetica Polonica. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.1- 1960- Volume(issue)/page/year: 26,109,1985

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332-H315-H319-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S36-S36/37/39

[ RIDADR ]:
2811

[ WGK Germany ]:
3

[ RTECS ]:
XS9550000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2921590090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2921590090

[ Summary ]:
2921590090. other aromatic polyamines and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Interaction with the aromatic hydrocarbon receptor, CYP1A induction, and mutagenicity of a series of diaminotoluenes: implications for their carcinogenicity.

Toxicol. Appl. Pharmacol. 139(1) , 203-11, (1996)

The present study was undertaken to provide a rationale for the marked difference in carcinogenic potential among isomeric diaminotoluenes, in relation to their ability to induce their own bioactivati...

Pd(II) and Pt(II) complexes with aromatic diamines: study of their interaction with DNA.

J. Inorg. Biochem. 98(3) , 510-21, (2004)

Pd(II) and Pt(II) new complexes with simple aromatic diamines were synthesised and characterised with the aim of studying their possible antitumour activity. The aromatic diamines chosen were 2,3-diam...