2-Amino-4-methylbenzonitrile

Names

[ Name ]:
2-Amino-4-methylbenzonitrile

[Synonym ]:
Benzonitrile, 2-amino-4-methyl-
2-Amino-4-methylbenzonitrile
4-methylanthranilonitrile
6-Cyano-m-toluidine
2-amino-4-methyl-benzonitrile
4-Methyl-2-nitro-benzonitrile
EINECS 248-020-0
4-METHYL-2-AMINOBENZONITRILE
MFCD00173706
2-Cyano-5-methylaniline
5-methyl-2-cyanoaniline
2-amino-4-methylbenzenecarbonitrile
3-Amino-4-cyanotoluene
2-Amino-4-methyl-benzonitril

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
301.2±30.0 °C at 760 mmHg

[ Melting Point ]:
92-95 °C(lit.)

[ Molecular Formula ]:
C₈H₈N₂

[ Molecular Weight ]:
132.163

[ Flash Point ]:
136.0±24.6 °C

[ Exact Mass ]:
132.068741

[ PSA ]:
49.81000

[ LogP ]:
1.86

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.576

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332-H315-H319-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S36-S36/37

[ RIDADR ]:
3439

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2926909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2926909090

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Synthesis, in vitro pharmacology, and molecular modeling of very potent tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease.

J. Med. Chem. 42(17) , 3227-42, (1999)

Eleven new 12-amino-6,7,10,11-tetrahydro-7, 11-methanocycloocta[b]quinoline derivatives [tacrine (THA)-huperzine A hybrids, rac-21-31] have been synthesized as racemic mixtures and tested as acetylcho...

Synthesis of 4-(Phenylamino) quinazoline-2 (1H)-selones and Diselenides from Isoselenocyanates: Dimroth Rearrangement of an Intermediate. Atanassov PK, et al.

Helv. Chim. Acta 87(7) , 1873-7, (2004)