Pomalidomide-5'-C8-acid

Names

[ Name ]:
Pomalidomide-5'-C8-acid

Biological Activity

[Description]:

Pomalidomide-5'-C8-acid (Compound 3d') is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide-5'-C8-acid can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

[References]

[1]. Rao, Yu, et al. Preparation of isoindoline derivatives as degradation agent targeting both BTK and GSPT1 proteins and its application. Patent. CN115304606

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₇N₃O₆

[ Molecular Weight ]:
429.47

Related Compounds

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