TRPV4 antagonist 3

Names

[ CAS No. ]:
2681273-35-6

[ Name ]:
TRPV4 antagonist 3

Biological Activity

[Description]:

TRPV4 antagonist 3 is a TRPV4 antagonist (pIC50 = 8.4).

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel

Research Areas >> Cardiovascular Disease

[References]

[1]. Patterson JR, et al. Design and Optimization of an Acyclic Amine Series of TRPV4 Antagonists by Electronic Modulation of Hydrogen Bond Interactions. J Med Chem. 2020 Dec 10;63(23):14867-14884.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₁₈F₄N₄O₃S

[ Molecular Weight ]:
470.44

Related Compounds

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