Cereblon inhibitor 1

Names

[ Name ]:
Cereblon inhibitor 1

Biological Activity

[Description]:

Cereblon inhibitor 1, an isoindoline derivative, is a cereblon E3 ubiquitin ligase modulating drug. Cereblon inhibitor 1 has the potential for cancer research[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> Ligand for E3 Ligase

[Target]

Cereblon

[In Vitro]

Cereblon inhibitor 1 (compound CM-48) suppresses MM.1S cell proliferation (IC50=0.0365 nM)[1].

[References]

[1]. Hui Liu, et al. Isoindoline derivative and its application. WO2021147889A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₂H₂₈ClF₂N₅O₄

[ Molecular Weight ]:
620.05

Related Compounds

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