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ritodrine

Names

[ CAS No. ]:
26652-09-5

[ Name ]:
ritodrine

[Synonym ]:
ritodrine
Yutopar S.R
Ritodrina
Utopar
Ritodrinium
Yutopar
Prepar

Biological Activity

[Description]:

Ritodrine (DU21220) is a β-adrenergic agonist, also an effective uterine relaxant, can be used for researching arrest premature labor[1][2].

[Related Catalog]:

Research Areas >> Endocrinology
Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor

[References]

[1]. Spellacy WN, et al. Treatment of premature labor with ritodrine: a randomized controlled study. Obstet Gynecol. 1979 Aug;54(2):220-3.

[2]. Canadian Preterm Labor Investigators Group. Treatment of preterm labor with the beta-adrenergic agonist ritodrine. N Engl J Med. 1992 Jul 30;327(5):308-12.

Chemical & Physical Properties

[ Density]:
1.213g/cm3

[ Boiling Point ]:
512.3ºC at 760mmHg

[ Molecular Formula ]:
C17H21NO3

[ Molecular Weight ]:
287.35400

[ Flash Point ]:
175.6ºC

[ Exact Mass ]:
287.15200

[ PSA ]:
72.72000

[ LogP ]:
2.74290

[ Vapour Pressure ]:
2.55E-11mmHg at 25°C

[ Index of Refraction ]:
1.618

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DA4797050
CHEMICAL NAME :
Benzenemethanol, 4-hydroxy-alpha-(1-((2-(4-hydroxyphenyl)ethyl)amino)e thyl)-, (R*,S*)-
CAS REGISTRY NUMBER :
26652-09-5
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C17-H21-N-O3
MOLECULAR WEIGHT :
287.39

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Multiple routes
DOSE :
21040 ug/kg
SEX/DURATION :
female 10-35 week(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system
REFERENCE :
EOGRAL European Journal of Obstetrics, Gynecology and Reproductive Biology. (Elsevier Science Pub. BV, POB 211, 1000 AE Amsterdam, Netherlands) V.3- 1973- Volume(issue)/page/year: 59,137,1995
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
DOSE :
3000 ug/kg
SEX/DURATION :
female 20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Maternal Effects - other effects
REFERENCE :
BMMBES Biochemical Medicine and Metabolic Biology. (Academic Press, Inc., Journal Customer Service, POB 6250, Duluth, MN 55802-0250) V.35- 1986- Volume(issue)/page/year: 52,128,1994

Related Compounds

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