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P-(1-Aziridinyl)-N-[(5-methoxy-2-pyrimidinyl)carbamoyl]phosphonamidic acid ethyl ester

Names

[ CAS No. ]:
26594-10-5

[ Name ]:
P-(1-Aziridinyl)-N-[(5-methoxy-2-pyrimidinyl)carbamoyl]phosphonamidic acid ethyl ester

[Synonym ]:
P-1-Aziridinyl-N-((5-methoxy-2-pyrimidinyl)carbamoyl)phosphonamidic acid ethyl ester
Phosphonamidic acid,P-1-aziridinyl-N-((5-methoxy-2-pyrimidinyl)carbamoyl)-,ethyl ester
N-Monoethyleneamidomonoethoxyphosphono-N'-5-methoxypyrimidyl-2-urea
ethyl n-[4-(aziridin-1-yl)-5-methoxypyrimidin-2-yl]-n-formylphosphorodiamidate
P-aziridin-1-yl-N-(5-methoxy-pyrimidin-2-ylcarbamoyl)-phosphonamidic acid ethyl ester

Chemical & Physical Properties

[ Density]:
1.469g/cm3

[ Boiling Point ]:
504ºC at 760 mmHg

[ Molecular Formula ]:
C10H16N5O4P

[ Molecular Weight ]:
301.23900

[ Flash Point ]:
258.6ºC

[ Exact Mass ]:
301.09400

[ PSA ]:
120.46000

[ LogP ]:
1.77250

[ Vapour Pressure ]:
2.76E-10mmHg at 25°C

[ Index of Refraction ]:
1.613

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SZ6180000
CHEMICAL NAME :
Phosphonamidic acid, P-1-aziridinyl-N-((5-methoxy-2-pyrimidinyl)carbamoyl) -, ethyl ester
CAS REGISTRY NUMBER :
26594-10-5
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H16-N5-O4-P
MOLECULAR WEIGHT :
301.28
WISWESSER LINE NOTATION :
T6N CNJ EO1 BMVMPO&O2&- AT3NTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 4,308,1970

Safety Information

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

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