PDE2A-IN-1

Names

[ CAS No. ]:
2648290-28-0

[ Name ]:
PDE2A-IN-1

Biological Activity

[Description]:

PDE2A-IN-1 is a phosphodiesterase 2A (PDE2A) inhibitor with an IC50 value of 1.3 nM.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)

Research Areas >> Neurological Disease

[References]

[1]. Tresadern G, et al. [1,2,4]Triazolo[1,5-a]pyrimidine Phosphodiesterase 2A Inhibitors: Structure and Free-Energy Perturbation-Guided Exploration. J Med Chem. 2020 Nov 12;63(21):12887-12910.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₂F₂N₆

[ Molecular Weight ]:
420.46

Related Compounds

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