AVSEHQLLHDKGKSIQDLRRRFFLHHLI-{Aib}-EIHTAYRFGG

Names

[ CAS No. ]:
2640019-27-6

[ Name ]:
AVSEHQLLHDKGKSIQDLRRRFFLHHLI-{Aib}-EIHTAYRFGG

Biological Activity

[Description]:

AVSEHQLLHDKGKSIQDLRRRFFLHHLI-{Aib}-EIHTAYRFGG promotes bone-ossification. AVSEHQLLHDKGKSIQDLRRRFFLHHLI-{Aib}-EIHTAYRFGG can be used in the research of diseases or disorders related to osteogenic defects or bone mineral density (BMD) decreasing, such as osteoporosis[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[In Vivo]

AVSEHQLLHDKGKSIQDLRRRFFLHHLI-{Aib}-EIHTAYRFGG (2.5 and 5 μg/kg, s.c.) promotes ossification in Ovariectomy (OVX)-induced osteoporosis rats[1]. Animal Model: Ovariectomy (OVX)-induced osteoporosis rats[1] Dosage: 2.5 μg/kg, 5 μg/kg Administration: Subcutaneous injection (s.c.) Result: Increased bone mineral density in thigh bone and lumbar vertebra.

[References]

[1]. Fu Guoqin, et al. Active polypeptide compound. Patent. WO2021068550.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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