MRTX-1719

Names

[ Name ]:
MRTX-1719

Biological Activity

[Description]:

MRTX-1719 is a potent first-in-class selective inhibitor of the PRMT5/MTA complex, with an IC50 of less than 10 nM in PRMT5/MTA MTAPDEL SDMA cells[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Epigenetics >> Histone Methyltransferase

[Target]

IC50: <10 nM (PRMT5/MTA MTAPDEL SDMA cells)[1].

[References]

[1]. Targeting the genetic and immunological drivers of cancer.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₁₈ClFN₆O₂

[ Molecular Weight ]:
464.88

Related Compounds

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