4-(4-chlorophenyl)-8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-thia-4,8-diazaspiro[4.5]decan-3-one,hydrochloride
Names
[ CAS No. ]:
26260-87-7
[ Name ]:
4-(4-chlorophenyl)-8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-thia-4,8-diazaspiro[4.5]decan-3-one,hydrochloride
[Synonym ]:
1-Thia-4,8-diazaspiro(4.5)decan-3-one,4-(4-chlorophenyl)-8-((2,3-dihydro-1,4-benzodioxin-2-yl)methyl)-,monohydrochloride
4-(4-chlorophenyl)-8-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-1-thia-4,8-diazaspiro[4.5]decan-3-one hydrochloride(1:1)
8-(1,4-Benzodioxan-2-ylmethyl)-4-(4-chlorophenyl)-3-oxo-1-thia-4,8-diazaspiro(4.5)decane HCl
Chemical & Physical Properties
[ Boiling Point ]:
654.8ºC at 760mmHg
[ Molecular Formula ]:
C22H24Cl2N2O3S
[ Molecular Weight ]:
467.40900
[ Flash Point ]:
349.8ºC
[ Exact Mass ]:
466.08800
[ PSA ]:
67.31000
[ LogP ]:
4.85680
[ Vapour Pressure ]:
5.05E-17mmHg at 25°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XI2277513
- CHEMICAL NAME :
- 1-Thia-4,8-diazaspiro(4.5)decan-3-one, 4-(4-chlorophenyl)-8-((2,3-dihydro-1,4- benzodioxin-2-yl)methyl)-, monohydrochloride
- CAS REGISTRY NUMBER :
- 26260-87-7
- LAST UPDATED :
- 199109
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C22-H23-Cl-N2-O3-S.Cl-H
- MOLECULAR WEIGHT :
- 467.44
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >500 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 91,798,1971