10H-Phenothiazine-10-ethanaminium,N,N,N,a-tetramethyl-, iodide (1:1)
Names
[ CAS No. ]:
26212-80-6
[ Name ]:
10H-Phenothiazine-10-ethanaminium,N,N,N,a-tetramethyl-, iodide (1:1)
[Synonym ]:
Trimethylammonium-isopropyl-phenthiazin jodid
Promethazin methoiodid
Promethazin-Methyliodid
Promethazine methiodide
Thiazinamium iodide
Promethazinum-methoiodide
Chemical & Physical Properties
[ Molecular Formula ]:
C18H23IN2S
[ Molecular Weight ]:
426.35800
[ Exact Mass ]:
426.06300
[ PSA ]:
28.54000
[ LogP ]:
1.45300
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BR8140000
- CHEMICAL NAME :
- Ammonium, (1-methyl-2-(phenothiazin-10-yl)ethyl)trimethyl-, iodide
- CAS REGISTRY NUMBER :
- 26212-80-6
- LAST UPDATED :
- 199203
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C18-H23-N2-S.I
- MOLECULAR WEIGHT :
- 426.39
- WISWESSER LINE NOTATION :
- T C666 BN ISJ B1Y1&K1&1&1 &Q &I
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,450,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 11 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,450,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 6 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,450,1959