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MS4322

Names

[ CAS No. ]:
2601727-80-2

[ Name ]:
MS4322

Biological Activity

[Description]:

MS4322 is a first-in-class PRMT5 degrader and a valuable chemical tool (PROTAC) for exploring the PRMT5 functions in health and disease.

[Related Catalog]:

Signaling Pathways >> PROTAC >> PROTAC

[Target]

VHL


[References]

[1]. Shen Y, et al. Discovery of First-in-Class Protein Arginine Methyltransferase 5 (PRMT5) Degraders. J Med Chem. 2020 Sep 10;63(17):9977-9989.

Chemical & Physical Properties

[ Molecular Formula ]:
C55H76N10O12S

[ Molecular Weight ]:
1101.32

Safety Information

[ Hazard Codes ]:
Xi


Related Compounds