Mecarbam
Names
[ CAS No. ]:
2595-54-2
[ Name ]:
Mecarbam
[Synonym ]:
Murphotox
MFCD00129669
Marfotoks
MECARBAM
Murfotox
S-(N-ethoxycarbonyl-N-methylcarbamoylmethyl) O,O-diethyl phosphorodithioate
Pestan
EINECS 219-993-9
Criotox
ethyl 6-ethoxy-2-methyl-3-oxo-7-oxa-5-thia-2-aza-6-phosphanonanoate 6-sulfide
Pennsalt TD-72
AFOS
Caswell No. 340
ethyl [(diethoxyphosphinothioylthio)acetyl](methyl)carbamate
Mercarbam
Mecarbame
ethyl (6Ξ)-6-ethoxy-2-methyl-3-oxo-6-sulfanylidene-7-oxa-5-thia-2-aza-6λ5-phosphanonan-1-oate
ethyl N-(2-diethoxyphosphinothioylsulfanylacetyl)-N-methylcarbamate
Chemical & Physical Properties
[ Density]:
1.265 g/cm3
[ Boiling Point ]:
421.4ºC at 760 mmHg
[ Melting Point ]:
<25℃
[ Molecular Formula ]:
C10H20NO5PS2
[ Molecular Weight ]:
329.37300
[ Flash Point ]:
>100 °C
[ Exact Mass ]:
329.05200
[ PSA ]:
132.27000
[ LogP ]:
3.28260
[ Vapour Pressure ]:
2.62E-07mmHg at 25°C
[ Index of Refraction ]:
1.523
[ Storage condition ]:
APPROX 4°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- FB3850000
- CHEMICAL NAME :
- Carbamic acid, (mercaptoacetyl)methyl-, ethyl ester, S-ester with O,O- diethyl phosphorodithioate
- CAS REGISTRY NUMBER :
- 2595-54-2
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C10-H20-N-O5-P-S2
- MOLECULAR WEIGHT :
- 329.40
- WISWESSER LINE NOTATION :
- 2OVN1&V1SPS&O2&O2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 31 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BOCKAF Bochu Kagaku. Scientific Pest Control. (Kyoto, Japan) V.1-42, 1937-77. Discontinued. Volume(issue)/page/year: 26,69,1961
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 700 mg/m3/6H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,538,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 380 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71. Discontinued. Volume(issue)/page/year: 9,119,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 36 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971 Volume(issue)/page/year: -,364,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 106 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GUCHAZ Guide to the Chemicals Used in Crop Protection. (Information Canada, 171 Slater St., Ottawa, Ont., Canada) Volume(issue)/page/year: 6,323,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 60 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BOCKAF Bochu Kagaku. Scientific Pest Control. (Kyoto, Japan) V.1-42, 1937-77. Discontinued. Volume(issue)/page/year: 26,69,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 65 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BOCKAF Bochu Kagaku. Scientific Pest Control. (Kyoto, Japan) V.1-42, 1937-77. Discontinued. Volume(issue)/page/year: 26,69,1961
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JEENAI Journal of Economic Entomology. (Entomological Soc. of America, 4603 Calvert Rd., College Park, MD 20740) V.1- 1908- Volume(issue)/page/year: 62,934,1969
Safety Information
[ Symbol ]:
GHS06, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H311-H410
[ Precautionary Statements ]:
P273-P280-P301 + P310-P312-P501
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T: Toxic;N: Dangerous for the environment;Xn: Harmful;F: Flammable;
[ Risk Phrases ]:
24/25-50/53-36-20/21/22-11
[ Safety Phrases ]:
36/37-45-60-61-36-26-16
[ RIDADR ]:
3018
[ WGK Germany ]:
3
[ RTECS ]:
FB3850000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1(a)
[ HS Code ]:
2930909064
Customs
[ HS Code ]: 2930909064
[ Summary ]:
2930909064 s-((n-(2-chlorophenyl)butyramido)methyl) o,o-dimethyl phosphorodithioate
Articles
Vet. Hum. Toxicol. 38(2) , 101-7, (1996)
Nine human acute poisonings due to intentional ingestion of organophosphorous pesticides are presented. Six of the victims died. Six patients were treated in the Intensive Care Unit (ICU) from 34 h to...
Gas chromatographic determination of mecarbam and its metabolites mecarboxon, diethoate, and diethoxon in cottonseeds.J. Assoc. Off. Anal. Chem. 70(5) , 870-4, (1987)
A gas chromatographic method is described for determining residues of mecarbam and 3 of its metabolites, mecarboxon, diethoate, and diethoxon, in cottonseeds. For mecarbam analysis, following Soxhlet ...
Mother-fetus postmortem toxicologic analysis in a fatal overdose with mecarbam.Forensic Sci. Int. 35(4) , 249-52, (1987)
A suicidal poisoning committed by a 19-year-old pregnant woman, who ingested an unknown quantity of an aqueous solution mecarbam (trade name includes 'Murfotox') containing 68 g/l of S-(N-ethoxycarbon...