Acetoxytriethyllead(IV)
Names
[ CAS No. ]:
2587-81-7
[ Name ]:
Acetoxytriethyllead(IV)
[Synonym ]:
Lead,acetoxytriethyl
MFCD00015100
Triethyllead acetate
Acetoxy-triaethyl-plumban
Acetoxy-triaethyl-blei
Plumbane,acetoxytriethyl
Acetoxytriethyllead
Triethylbleiacetat
Acetoxytriethylplumbane
Triaethylbleiacetat
Chemical & Physical Properties
[ Melting Point ]:
155ºC (dec.)(lit.)
[ Molecular Formula ]:
C8H18O2Pb
[ Molecular Weight ]:
353.42700
[ Exact Mass ]:
354.10700
[ PSA ]:
26.30000
[ LogP ]:
2.55470
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TP3922000
- CHEMICAL NAME :
- Plumbane, acetoxytriethyl-
- CAS REGISTRY NUMBER :
- 2587-81-7
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C8-H18-O2-Pb
- MOLECULAR WEIGHT :
- 353.45
- WISWESSER LINE NOTATION :
- 1VO-PB-2&2&2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 57 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 30 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 15 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 14 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 65 mg/kg/13W-I
- TOXIC EFFECTS :
- Spinal Cord - other degenerative changes Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 120 mg/kg/19W-I
- TOXIC EFFECTS :
- Brain and Coverings - other degenerative changes
MUTATION DATA
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 6 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 298,1,1992
Safety Information
[ Hazard Codes ]:
T+: Very toxic;N: Dangerous for the environment;
[ Risk Phrases ]:
R61;R26/27/28;R33;R50/53;R62
[ Safety Phrases ]:
S45;S53;S60;S61
[ RIDADR ]:
UN 2811
[ WGK Germany ]:
3
[ RTECS ]:
TP3922000
[ HS Code ]:
2915299090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2915299090
[ Summary ]:
2915299090 salts of acetic acid。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:50.0%