ND1-YL2

Names

[ CAS No. ]:
2582803-80-1

[ Name ]:
ND1-YL2

Biological Activity

[Description]:

ND1-YL2 is a PROTAC that selectively degrades SRC-1 via the N-degron pathway. ND1-YL2 significantly inhibits cancer invasion and migration in vitro and in vivo. ND1-YL2 can be used in cancer research[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC

[Target]

SRC-1[1].


[References]

[1]. Lee Y, et al. Targeted Degradation of Transcription Coactivator SRC-1 through the N-Degron Pathway. Angew Chem Int Ed Engl. 2020 Sep 28;59(40):17548-17555.  

Chemical & Physical Properties

[ Molecular Formula ]:
C114H189N27O28

[ Molecular Weight ]:
2385.88

Related Compounds