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M190S

Names

[ CAS No. ]:
2578300-07-7

[ Name ]:
M190S

Biological Activity

[Description]:

M109S is a novel small molecule protecting cells from mitochondria-dependent apoptosis both in vitro and in vivo. M109S has the potential to become a research tool for studying cell death mechanisms and to develop therapeutics targeting mitochondria-dependent cell death pathway. M109S has orally bioactivity with excellent brain permeability[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Apoptosis >> Caspase

[Target]

caspase-3:23.4 nM (EC50)

Caspase 3:23.4 nM (EC50)


[References]

[1]. Mieko Matsuyama, et al. Development of novel cytoprotective small compounds inhibiting mitochondria-dependent cell death. Science 26, 107916, October 20, 2023

Chemical & Physical Properties

[ Molecular Formula ]:
C21H21N5O2

[ Molecular Weight ]:
375.42


Related Compounds

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