VD2173

Names

[ Name ]:
VD2173

Biological Activity

[Description]:

VD2173 is a side chain cyclized macrocyclic peptide inhibitor of HGF-activating serine proteases. VD2173 potently inhibits matriptase and hepsin. VD2173 can be used for the research of lung cancer[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease

Research Areas >> Cancer

[References]

[1]. Damalanka VC, et, al. Macrocyclic Inhibitors of HGF-Activating Serine Proteases Overcome Resistance to Receptor Tyrosine Kinase Inhibitors and Block Lung Cancer Progression. J Med Chem. 2021 Dec 23;64(24):18158-18174.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₁H₄₅N₉O₆S

[ Molecular Weight ]:
671.81

Related Compounds

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