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MEK4 inhibitor 6ff

Names

[ CAS No. ]:
2570386-33-1

[ Name ]:
MEK4 inhibitor 6ff

Biological Activity

[Description]:

MEK4 inhibitor 6ff is potent, selective MEK4 inhibitor with IC50 of 66 nM.MEK4 inhibitor 6ff displays excellent selectivity across the entire MEK family, 150-fold more potent against MEK4 than any other MEKkinase, and is at least 385-fold selective against three other MEK kinases.

[References]

1. Kristine K Deibler, et al. ChemMedChem. 2019 Mar 22;14(6):615-620.

Chemical & Physical Properties

[ Molecular Formula ]:
C14H9FN2O2

[ Molecular Weight ]:
256.236


Related Compounds

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