N-Benzyl-2-chloroacetamide

Names

[ Name ]:
N-Benzyl-2-chloroacetamide

[Synonym ]:
N-Benzyl-2-chloroacetamide
2'-chloro-benzylacetanilide
N-(Chloroacetyl)benzylamine
ClCH2CONHBn
Acetamide,N-benzyl-2-chloro
2-Chloro-N-benzylacetamide
N-benzyl-2-chloroethanamide
2-Chloro-N-(phenylmethyl)acetamide
Acetamide,2-chloro-N-(phenylmethyl)
Acetamide, 2-chloro-N-(phenylmethyl)-
N-benzyl-2-chloro-acetamide
MFCD00084929
N-Benzylchloroacetamide

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
367.5±35.0 °C at 760 mmHg

[ Melting Point ]:
93-96 °C(lit.)

[ Molecular Formula ]:
C₉H₁₀ClNO

[ Molecular Weight ]:
183.635

[ Flash Point ]:
176.0±25.9 °C

[ Exact Mass ]:
183.045090

[ PSA ]:
29.10000

[ LogP ]:
1.02

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.539

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AB4546570

CHEMICAL NAME :: Acetamide, N-benzyl-2-chloro-

CAS REGISTRY NUMBER :: 2564-06-9

BEILSTEIN REFERENCE NO. :: 2091813

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H10-Cl-N-O

MOLECULAR WEIGHT :: 183.65

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 290 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 2 mg/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 172,29,1986

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
AB4546570

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Synthesis, computational studies and preliminary pharmacological evaluation of 2-[4-(aryl substituted) piperazin-1-yl]-N-benzylacetamides as potential antipsychotics. Kumar S, et al.

Arabian Journal of Chemistry , (2012)

Formation and Characterization of Gallium (III) Complexes with Monoamide Derivatives of 1,4,7-Triazacyclononane-1,4,7-triacetic Acid: A Study of the Dependency of Structure on Reaction pH. Shetty D, et al.

Eur. J. Inorg. Chem. 2010(34) , 5432-5438, (2010)

Bis [N-benzyl-2-(quinolin-8-yloxy) acetamide] monohydrate. Wang MS, et al.

Acta Crystallogr. Sect. E Struct. Rep. Online 67(7) , o1558, (2011)