5-Chlorooxindole

Names

[ Name ]:
5-Chlorooxindole

[Synonym ]:
7-CHLORO-1,3-DIHYDRO-2H-INDOL-2-ONE
5-Chlorooxindole
2H-Indol-2-one, 5-chloro-1,3-dihydro-
7-chloro-1,3-dihydroindol-2-one
5-chloroindolin-2-one
5-Chloro-1,3-dihydro-2H-indol-2-one
2H-Indol-2-one, 7-chloro-1,3-dihydro-
7-Chloroindolin-2-one

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
341.0±42.0 °C at 760 mmHg

[ Melting Point ]:
221-225ºC

[ Molecular Formula ]:
C₈H₆ClNO

[ Molecular Weight ]:
167.592

[ Flash Point ]:
160.0±27.9 °C

[ Exact Mass ]:
167.013794

[ PSA ]:
29.10000

[ LogP ]:
1.35

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.602

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
61

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933790090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933790090

[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

Articles

Assay and purity evaluation of 5-chlorooxindole by liquid chromatography.

J. Pharm. Biomed. Anal. 14(7) , 825-33, (1996)

5-Chlorooxindole (5-CO) is a starting material for tenidap sodium, a pharmaceutical drug candidate produced by Pfizer. To insure potency and purity of the drug substance, it is necessary to demonstrat...