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thiazfluron

Names

[ CAS No. ]:
25366-23-8

[ Name ]:
thiazfluron

[Synonym ]:
1,3-dimethyl-1-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]urea
Thiazfluron
2-(N,N'-Dimethylureido)-5-trifluoromethyl-1,3,4-thiadiazole
Thiazafluron [BSI:ISO]
Erbotan
1,3-dimethyl-3-(5-trifluoromethyl-1,3,4-thiadiazol-2-yl)urea
MFCD00078722
1,3-dimethyl-1-(5-trifluoromethyl-1,3,4-thiodiazol-2-yl)urea
1-methyl-3-methyl-3-(5-trifluoromethyl-1,3,4-thiadiazol-2-yl)urea
EINECS 246-901-4
N,N’-dimethyl-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]urea
1,3-dimethyl-1-(5-trifluoromethyl-1,3,4-thiadiazol-2-yl)urea
1-(5-trifluoromethyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea
N-[5-Trifluoromethyl-1,3,4-thiadiazol-2-yl]-N,N'-dimethyl urea
1,3-dimethyl-1-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yl)-urea
Dmttu

Chemical & Physical Properties

[ Density]:
1.507g/cm3

[ Melting Point ]:
136.5°C

[ Molecular Formula ]:
C6H7F3N4OS

[ Molecular Weight ]:
240.20600

[ Exact Mass ]:
240.02900

[ PSA ]:
86.36000

[ LogP ]:
1.72340

[ Index of Refraction ]:
1.519

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XI3760000
CHEMICAL NAME :
1,3,4-Thiadiazole, 2-(N,N'-dimethylureido)-5-trifluoromethyl-
CAS REGISTRY NUMBER :
25366-23-8
LAST UPDATED :
199612
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C6-H7-F3-N4-O-S
MOLECULAR WEIGHT :
240.23
WISWESSER LINE NOTATION :
T5NN DSJ CXFFF EMVN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
278 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,811,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,811,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
630 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A392,1983 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3276 mg/kg/13W-C
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Related to Chronic Data - death Related to Chronic Data - changes in ovarian weight
REFERENCE :
NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 18,S225,1993 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
100 mg/kg
SEX/DURATION :
female 6-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - other effects to embryo
REFERENCE :
NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 18,S225,1993
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
200 mg/kg
SEX/DURATION :
female 6-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
REFERENCE :
NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 18,S225,1993

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H410

[ Precautionary Statements ]:
P273-P501

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;N: Dangerous for the environment;

[ Risk Phrases ]:
22-50/53

[ Safety Phrases ]:
60-61

[ RIDADR ]:
UN 2811 6.1/PG 3

[ RTECS ]:
XI3760000

[ HS Code ]:
29349990

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