Fazpilodemab

Names

[ Name ]:
Fazpilodemab

Biological Activity

[Description]:

Fazpilodemab (BFKB8488A) is a humanized, agonistic, bispecific antibody targeting fibroblast growth factor receptor 1c (FGFR1c) and Klothoβ. Fazpilodemab can be used for the research of type 2 diabetes mellitus (T2DM) or nonalcoholic fatty liver disease (NAFLD)[1].

[Related Catalog]:

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FGFR

Research Areas >> Metabolic Disease

[Target]

FGFR1c

Klothoβ

[References]

[1]. Wong C, et al. Fibroblast growth factor receptor 1/Klothoβ agonist BFKB8488A improves lipids and liver health markers in patients with diabetes or NAFLD: A phase 1b randomized trial. Hepatology. 2022 Aug 22.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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