SH379

Names

[ Name ]:
SH379

Biological Activity

[Description]:

SH379 is the derivative of 2-methylpyrimidine-fused tricyclic diterpene. SH379 is a potent and orally active anti-late-onset hypogonadism agent. SH379 significantly promotes the expression of the key testosterone synthesis-related enzymes StAR and 3β-HSD. SH379 stimulates autophagy through regulating AMPK/mTOR signaling pathway[1].

[Related Catalog]:

Research Areas >> Endocrinology

Signaling Pathways >> Autophagy >> Autophagy

[References]

[1]. Bai J, et al. Synthesis and biological evaluation of methylpyrimidine-fused tricyclic diterpene analogs as novel oral anti-late-onset hypogonadism agents. Eur J Med Chem. 2019;176:21-40.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₉N₃O₂

[ Molecular Weight ]:
379.50

Related Compounds

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