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BPR1R024

Names

[ CAS No. ]:
2503015-75-4

[ Name ]:
BPR1R024

Biological Activity

[Description]:

BPR1R024 is an orally active and selective CSF1R inhibitor (IC50 = 0.53 nM).

[Related Catalog]:

Research Areas >> Cancer
Research Areas >> Inflammation/Immunology
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Fms

[References]

[1]. Lee KH, et al. Discovery of BPR1R024, an Orally Active and Selective CSF1R Inhibitor that Exhibits Antitumor and Immunomodulatory Activity in a Murine Colon Tumor Model. J Med Chem. 2021 Oct 14;64(19):14477-14497.

Chemical & Physical Properties

[ Molecular Formula ]:
C24H21F3N6O2

[ Molecular Weight ]:
482.46

Related Compounds