7-Hydroxy-5-methyl-1,3,4-triazaindolizine

Names

[ Name ]:
7-Hydroxy-5-methyl-1,3,4-triazaindolizine

[Synonym ]:
Trapidil interMediate product
7-Hydroxy-5-methyl-1
6-Methyl-4-hydroxy-1,3,3a,7-tetraazaindene
5-Methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-ol
EINECS 219-706-7
5-Hydroxy-7-methyl-1,3,8-triazaindolizin
5-Methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol
7-Hydroxy-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine
5-Methyl-1,3,4-triazaindolizine-7-ol
Triazaindolizine
7-Hydroxy-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine
5-METHYL-(1,2,4)TRIAZOLO(1,5-A)PYRIMIDIN-7-OL
5-methyl-1,2,4-triazolo[1,5-a]pyrimidine-7(4H)-one
5-methyl-[1,2,4]-triazolo-[1,5-a]-pyrimidin-7-ol
Methyl hydroxytriazaindolizine
4-Hydroxy-6-methyl-1,3,3a,7-tetraazaindene
5-Methyl-s-trazolo[1,5-]pyrimidin-7-ol
4-hydroxy-6-methyl-1,3,3a,7-tetraza-indene
5-Methyl-1,2,4-Triazolo[1,5-a]Pyrimidin-7-ol
MFCD00005555

Chemical & Physical Properties

[ Density]:
1.424g/cm3

[ Melting Point ]:
280-283 °C(lit.)

[ Molecular Formula ]:
C₆H₆N₄O

[ Molecular Weight ]:
150.13800

[ Exact Mass ]:
150.05400

[ PSA ]:
63.31000

[ LogP ]:
0.13830

[ Index of Refraction ]:
1.699

[ Water Solubility ]:
INSOLUBLE IN COLD WATER

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XZ6133300

CHEMICAL NAME :: (1,2,4)Triazolo(1,5-a)pyrimidin-7-ol, 5-methyl-

CAS REGISTRY NUMBER :: 2503-56-2

LAST UPDATED :: 199706

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C6-H6-N4-O

MOLECULAR WEIGHT :: 150.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >450 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 13,597,1977

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P305 + P351 + P338

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
XZ6133300

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%