OSM-SMI-10B

Names

[ CAS No. ]:
2502294-55-3

[ Name ]:
OSM-SMI-10B

Biological Activity

[Description]:

OSM-SMI-10B a derivative of OSM-SMI-10. OSM-SMI-10B significantly reduces OSM-induced STAT3 phosphorylation in cancer cells upon co-incubation with OSM (Oncostatin M)[1].

[Related Catalog]:

Signaling Pathways >> Stem Cell/Wnt >> STAT
Research Areas >> Cancer
Signaling Pathways >> JAK/STAT Signaling >> STAT

[Target]

p-STAT3


[References]

[1]. Mass OA, et al. Bioactive recombinant human oncostatin M for NMR-based screening in drug discovery. Sci Rep. 2021 Aug 10;11(1):16174.  

Chemical & Physical Properties

[ Molecular Formula ]:
C21H14O7

[ Molecular Weight ]:
378.33

Related Compounds