(S,R,S)-AHPC-C7-amine hydrochloride

Names

[ CAS No. ]:
2502189-41-3

[ Name ]:
(S,R,S)-AHPC-C7-amine hydrochloride

Biological Activity

[Description]:

(S,R,S)-AHPC-C7-amine (VH032-C7-amine) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for estrogen-related receptor α (ERRα) PROTAC degrader[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

[References]

[1]. Lijie Peng, et al. Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation. ACS Med Chem Lett. 2019 Apr 12;10(5):767-772.  

[2]. Nello Mainolfi, et al. Stat degraders and uses thereof. Patent. WO2020206424A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C30H46ClN5O4S

[ Molecular Weight ]:
608.24

Related Compounds

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