RMS3

Names

[ CAS No. ]:
2497686-66-3

[ Name ]:
RMS3

Biological Activity

[Description]:

RMS3, a tetrandrine analogue, is a potent P-glycoprotein (P-gp) inhibitor. RMS3 has markedly antiproliferative and cytotoxic effects on cancer cells. RMS3 causes PARP cleavage, a marker for cells undergoing apoptosis. RMS3 has strong anticancer property[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer
Signaling Pathways >> Membrane Transporter/Ion Channel >> P-glycoprotein

[References]

[1]. RamonaSchütz, et al. Synthesis, biological evaluation and toxicity of novel tetrandrine analogues. Eur J Med Chem. 2020 Dec 1;207:112810.

Chemical & Physical Properties

[ Molecular Formula ]:
C38H39F3N2O6

[ Molecular Weight ]:
676.72

Related Compounds

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