Betifisolimab

Names

[ CAS No. ]:
2460539-60-8

[ Name ]:
Betifisolimab

Biological Activity

[Description]:

Betifisolimab (MSB-2311) is a humanized monoclonal antibody directed against the immunosuppressive ligand PD-L1. Betifisolimab has the potential for advanced solid tumors and hematological malignancies research[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Immunology/Inflammation >> PD-1/PD-L1

[In Vitro]

Betifisolimab (MSB-2311) 是一种人源化 PD-L1 抗体，具有独特的 pH 依赖性抗原结合特性，可实现肿瘤内循环并增强肿瘤渗透[1]。

[References]

[1]. Xichun Hu, et al. MSB2311, an anti-programmed death-ligand 1 antibody, in advanced solid tumors and hematological malignancies: Safety and tolerability, early anti-cancer activities from a phase I study in Chinese patients. Journal of Clinical Oncology 38, no. 15_suppl.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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