PROTAC eEF2K degrader-1

Names

[ CAS No. ]:
2458170-54-0

[ Name ]:
PROTAC eEF2K degrader-1

Biological Activity

[Description]:

PROTAC eEF2K degrader-1 (Compound 11l) is an eEF2K-Targeting PROTAC small molecule that induces apoptosis in MDA-MB-231 cells. PROTAC eEF2K degrader-1 mediates eEF2K degradation[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC

[References]

[1]. Yao Liu, et al. Designing an eEF2K-Targeting PROTAC small molecule that induces apoptosis in MDA-MB-231 cells. Eur J Med Chem. 2020 Oct 15;204:112505.

Chemical & Physical Properties

[ Molecular Formula ]:
C31H33N9O11

[ Molecular Weight ]:
707.65

Related Compounds