2-Ethyl-6-methylaniline
Names
[ CAS No. ]:
24549-06-2
[ Name ]:
2-Ethyl-6-methylaniline
[Synonym ]:
EINECS 246-309-6
2-Methyl-6-ethylaniline
2-Ethyl-6-methylaniline
6-Ethyl-2-toluidine
Benzenamine,2-ethyl-6-methyl
o-Toluidine,6-ethyl
ZR B2 F1
2-ethyl-6-methyl-phenylamine
2-Ethyl-6-methylbenzenamine
6-Ethyl-o-toluidine
Aniline,2-methyl-6-ethyl
2-ethyl-5-methylphenylamine
2-Methyl-6-ethylaniline (MEA)
6-methyl-2-ethyl-aniline
Benzenamine, 2-ethyl-6-methyl-
MFCD00007752
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
228.3±9.0 °C at 760 mmHg
[ Melting Point ]:
−33 °C(lit.)
[ Molecular Formula ]:
C9H13N
[ Molecular Weight ]:
135.206
[ Flash Point ]:
89.4±0.0 °C
[ Exact Mass ]:
135.104797
[ PSA ]:
26.02000
[ LogP ]:
2.39
[ Vapour Pressure ]:
0.1±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.550
[ Storage condition ]:
-20°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BY5600000
- CHEMICAL NAME :
- Aniline, 2-methyl-6-ethyl-
- CAS REGISTRY NUMBER :
- 24549-06-2
- BEILSTEIN REFERENCE NO. :
- 2079468
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C9-H13-N
- MOLECULAR WEIGHT :
- 135.23
- WISWESSER LINE NOTATION :
- ZR B2 F1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 885 mg/kg
- TOXIC EFFECTS :
- Liver - other changes Blood - changes in bone marrow (not otherwise specified) Blood - changes in spleen
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2200 mg/m3/4H
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 930 mg/kg
- TOXIC EFFECTS :
- Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - muscle weakness Behavioral - ataxia
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 700 mg/kg
- TOXIC EFFECTS :
- Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - muscle weakness Behavioral - ataxia
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2210 mg/kg/10D-C
- TOXIC EFFECTS :
- Blood - changes in bone marrow (not otherwise specified)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10200 mg/kg/6W-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes in urine composition Blood - changes in erythrocyte (RBC) count Nutritional and Gross Metabolic - changes in chlorine
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 8300 nmol/plate
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 211,279,1988
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302-H331
[ Precautionary Statements ]:
P261-P311
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R20/21/22
[ Safety Phrases ]:
S24/25-S23
[ RIDADR ]:
2810
[ WGK Germany ]:
2
[ RTECS ]:
BY5600000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921493000
[ Summary ]:
HS: 2921493000. 2-ethyl-6-methylaniline. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tarrif:4.0%. general tariff:11.0%
Articles
Environ. Pollut. 134(3) , 525-34, (2005)
In this work the degradation of the herbicides metolachlor, diuron, monuron and of the metabolites 2-ethyl-6-methylaniline (EMA), and 3,4-dichloroaniline (DCA) was assessed in laboratory experiments o...
Resolution of< i> N</i>-(2-ethyl-6-methylphenyl) alanine via free and immobilized lipase from< i> Pseudomonas cepacia</i>. Zheng L, et al.J. Mol. Catal., B Enzym. 38(3) , 119-25, (2006)