K-80001

Names

[ CAS No. ]:
242800-40-4

[ Name ]:
K-80001

Biological Activity

[Description]:

K-80001 is an RXRα-binder and COX-1/2 inhibitor, with IC50s of with an IC50 of 82.9μM, 3.4μM, 1.2μM for RXRα, COX-1 and COX-2, respectively[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology
Signaling Pathways >> Immunology/Inflammation >> COX
Signaling Pathways >> Metabolic Enzyme/Protease >> RAR/RXR

[References]

[1]. Zhou H, et.al. NSAID sulindac and its analog bind RXRalpha and inhibit RXRalpha-dependent AKT signaling. Cancer Cell. 2010 Jun 15;17(6):560-73.  

Chemical & Physical Properties

[ Molecular Formula ]:
C20H17FO2

[ Molecular Weight ]:
308.35

Related Compounds

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