PFI-5

Names

[ Name ]:
PFI-5

Biological Activity

[Description]:

PFI-5 a highly biochemically potent, selective, and cell-active SMYD2 chemical probe with IC50 of 8 nM.PFI-5 inhibits p53 methylation in MCF7 cells with EC50 of 1.3 uM, with no toxicity.

[References]

1. Taylor AP, et al. J Med Chem. 2019 Sep 12;62(17):7669-7683.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₃₉N₇O

[ Molecular Weight ]:
501.679

Related Compounds

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