hCAI/II-IN-1

Names

[ CAS No. ]:
2422028-82-6

[ Name ]:
hCAI/II-IN-1

Biological Activity

[Description]:

hCAI/II-IN-1 (Compound 3h) is a human carbonic anhydrase I and II (hCA I/II) inhibitor with IC50 values of 0.047 µM and 0.024 µM against hCA I and hCA II, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase

[Target]

IC50: 0.024 µM (hCA II), 0.047 µM (hCA I)[1] Ki: 0.013 µM (hCA II), 0.032 µM (hCA I)[1]


[References]

[1]. Sağlık BN, et al. Synthesis, characterization and carbonic anhydrase I and II inhibitory evaluation of new sulfonamide derivatives bearing dithiocarbamate. Eur J Med Chem. 2020 Jul 15;198:112392.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H29N5O3S3

[ Molecular Weight ]:
459.65

Related Compounds