anti-TNBC agent-2

Names

[ CAS No. ]:
2422001-22-5

[ Name ]:
anti-TNBC agent-2

Biological Activity

[Description]:

anti-TNBC agent-2 an anti-Triple negative breast cancer (TNBC) purine derivative. anti-TNBC agent-2 induces MDA-MB-231 cells apoptosis, and inhibits its migration and angiogenesis. anti-TNBC agent-2 inhibits tumor growth and metastasis and reduces the expression of Ki67 and CD31 protein in TNBC xenograft models. anti-TNBC agent-2 can be used for Triple negative breast cancer (TNBC) research[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer

[References]

[1]. Zhang Q, et al. Synthesis and mechanism of action of new purine derivatives against triple negative breast cancer. Eur J Med Chem. 2023 Sep 7;261:115797.  

Chemical & Physical Properties

[ Molecular Formula ]:
C28H37ClFN7O

[ Molecular Weight ]:
542.09

Related Compounds

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