NF-κB/PON1-IN-1

Names

[ CAS No. ]:
2419107-97-2

[ Name ]:
NF-κB/PON1-IN-1

Biological Activity

[Description]:

NF-κB/PON1-IN-1 (Compound 16) is a NF-κB/PON1 pathway inhibitor. NF-κB/PON1-IN-1 has antioxidant (IC50 = 45.76 µM) and hepatoprotective activities[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS

[Target]

IC50: 45.76 µM (antioxidant activity)[1]


[References]

[1]. Soliman AM, et al. Antioxidant activity of novel quinazolinones bearing sulfonamide: Potential radiomodulatory effects on liver tissues via NF-κB/ PON1 pathway. Eur J Med Chem. 2020 Jul 1;197:112333.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H16N6O4S2

[ Molecular Weight ]:
468.51

Related Compounds