KYT-1

Names

[ Name ]:
KYT-1

Biological Activity

[Description]:

KYT-1 is a potent, selective inhibitor of P. gingivalis virulence factor Arg-gingipain (Rgp) with Ki 40 nM (RgpA/B).KYT-1 showed significant inhibitory effects on SMC proliferation stimulated by Porphyromonas gingivalis.

[References]

1. Kadowaki T, et al. Mol Pharmacol. 2004 Dec;66(6):1599-606. 2. Hosn KN, et al. Clin Exp Dent Res. 2015 Oct 27;1(1):18-25. 3. Inaba H, et al. J Periodontol. 2011 Nov;82(11):1616-22. 4. Cao C, et al. Int J Clin Exp Med. 2015 Oct 15;8(10):18327-34.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₄₉N₉O₆

[ Molecular Weight ]:
619.768

Related Compounds

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