PROTAC BRD4 Degrader-13

Names

[ Name ]:
PROTAC BRD4 Degrader-13

Biological Activity

[Description]:

PROTAC BRD4 Degrader-13 (compound 9d) is a potent chimeric BRD4 degrader. PROTAC BRD4 Degrader-13 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.025 nM and 6.0 nM, respectively.

Chemical & Physical Properties

[ Molecular Formula ]:
C₆₈H₈₅F₂N₁₁O₁₇P₂S₂

[ Molecular Weight ]:
1492.54

[ Storage condition ]:
2-8°C

Related Compounds

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