PROTAC BRD4 Degrader-9

Names

[ Name ]:
PROTAC BRD4 Degrader-9

Biological Activity

[Description]:

PROTAC BRD4 Degrader-9 (compound 8a) is a potent BRD4 degrader. PROTAC BRD4 Degrader-9 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.86 nM and 7.6 nM, respectively.

Chemical & Physical Properties

[ Molecular Formula ]:
C₅₉H₇₁F₂N₉O₁₅S₄

[ Molecular Weight ]:
1312.50

[ Storage condition ]:
2-8°C

Related Compounds

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