hCA I-IN-1

Names

[ CAS No. ]:
2417232-26-7

[ Name ]:
hCA I-IN-1

Biological Activity

[Description]:

hCA I-IN-1 (Compound 6q) is a human carbonic anhydrase I (hCA I) inhibitor with Ki values of 38.3, 716.4, 940.1 and 192.8 nM against hCA I, hCA II, hCAIX and hCAXII, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase

[Target]

Ki: 38.3 nM (hCA I), 192.8 nM (hCAXII), 716.4 nM (hCA II), 940.1 nM (hCA IX)[1]


[References]

[1]. Singh P, et al. Synthesis and carbonic anhydrase inhibition studies of sulfonamide based indole-1,2,3-triazole chalcone hybrids. Bioorg Chem. 2020 Jun;99:103839.

Chemical & Physical Properties

[ Molecular Formula ]:
C27H23N5O4S

[ Molecular Weight ]:
513.57

Related Compounds