GNE-6893

Names

[ CAS No. ]:
2415374-98-8

[ Name ]:
GNE-6893

Biological Activity

[Description]:

GNE-6893 is a potent and orally active HPK1 inhibitor. GNE-6893 can be used in research of cancer[1].

[Related Catalog]:

Signaling Pathways >> MAPK/ERK Pathway >> MAP4K

Research Areas >> Cancer

[Target]

HPK1

[References]

[1]. Andreas S, et, al. A Convergent Synthesis of HPK1 Inhibitor GNE-6893 via Palladium-Catalyzed Functionalization of a Tetrasubstituted Isoquinoline. Org. Process Res. Dev. 2023;27(3):523-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₄FN₅O₄

[ Molecular Weight ]:
453.47