Cyclopropaneacetamide-Exatecan

Names

[ CAS No. ]:
2414254-36-5

[ Name ]:
Cyclopropaneacetamide-Exatecan

Biological Activity

[Description]:

Cyclopropaneacetamide-Exatecan (Compound 2-A) is an ADC Cytotoxin and an Exatecan analogue. Cyclopropaneacetamide-Exatecan can be used in the synthesis of ADC such as anti-B7H3 antibody-Exatecan analogue conjugate (compound ADC-2)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Cytotoxin

[References]

[1]. Ying Hua, et al. Anti-b7h3 antibody-exatecan analog conjugate and medicinal use thereof. Patent WO2020063673A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C29H28FN3O6

[ Molecular Weight ]:
533.55