(S,R,S)-AHPC-C10-NHBoc

Names

[ CAS No. ]:
2412055-13-9

[ Name ]:
(S,R,S)-AHPC-C10-NHBoc

Biological Activity

[Description]:

(S,R,S)-AHPC-C10-NHBoc is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC (HY-125845) based VHL ligand and a linker used for BET-Targeted PROTAC[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

[References]

[1]. Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2020 Jan 7;15(1):17-25.  

Chemical & Physical Properties

[ Molecular Formula ]:
C38H59N5O6S

[ Molecular Weight ]:
713.97

Related Compounds